Global COVID-19 prevention trial of hydroxychloroquine to resume

US President Donald Trump said in March hydroxychloroquine could be a game-changer and then said he was taking it himself (Photo: iStock)

A world trial designed to take a look at whether or not the anti-malaria medication hydroxychloroquine and chloroquine can save you an infection with COVID-19 is to restart after being authorized via British regulators.

The Medicines and Healthcare Products Regulatory Agency (MHRA) took its determination on what’s referred to as the COPCOV trial after hydroxychloroquine was once present in every other British trial to haven’t any receive advantages as a remedy for sufferers already inflamed with COVID-19, the illness led to via the brand new coronavirus.

The COPCOV learn about was once paused pending evaluate after the remedy trial effects.

It is a randomised, placebo-controlled trial this is aiming to enrol 40,000 healthcare staff and different at-risk team of workers world wide, and is being led via the Oxford University’s Mahidol Oxford Tropical Medicine Research Unit (MORU) within the Thai capital, Bangkok.

US President Donald Trump mentioned in March hydroxychloroquine is usually a game-changer after which mentioned he was once taking it himself, even after the United States regulator, the Food and Drug Administration (FDA), instructed that its efficacy and protection had been unproven.

The FDA later revoked emergency use authorisation for the medicine to deal with COVID-19, after trials confirmed they had been of no receive advantages as therapies.

But White, who’s co-leadng the COPCOV trial, mentioned research of the medicine as a possible preventative drugs had now not but given a conclusive solution.

“Hydroxychloroquine could still prevent infections, and this needs to be determined in a randomised controlled trial,” he mentioned in a commentary. “The question whether (it) can prevent COVID-19 or not remains as pertinent as ever.”

White’s staff mentioned recruitment of British well being staff would resume this week, and mentioned plans had been below manner for brand spanking new websites in Thailand and Southeast Asia, Africa and South America. Results are anticipated via the top of this yr. (Reporting via Kate Kelland, enhancing via Paul Sandle and Timothy Heritage)

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